Setting up the source document
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Use template styles for every heading and paragraph
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Add alternative text for every image
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Use column and/or row headers for tables and add a caption or intro text
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Make sure links make sense out of context (no “click here”)
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Use short URLs; be considerate to screen reader users
Screen captures in this section from http://blogs.adobe.com/accessibility/assets/WordToPDFReferenceCard_v1.pdf